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View SNV signature attributions associated with CESAnalysis samples.

Usage

get_signature_weights(cesa = NULL, raw = F, artifacts_zeroed = NULL)

Arguments

cesa

CESAnalysis object

raw

Default FALSE. When TRUE, return raw signature attributions as found by the signature extraction tool. Format may vary by tool.

artifacts_zeroed

Deprecated.

Value

A data.table of signature attributions for each sample. By default, these are estimated relative weights of biologically-associated signatures (i.e., non-artifact signatures) that sum to 1.

Details

Use raw = TRUE to get signature attributions as produced by the signature extraction tool (or as provided by the user with set_signature_weights()), without any of the adjustments that are made by cancereffectsizeR's trinuc_mutation_rates().