Tissue-specific mutational signature exclusions — suggest_cosmic_signature

Get suggestions on signatures_to_remove for trinuc_mutation_rates for COSMIC signatures v3 and later. For details, see this article on our website.

Usage

suggest_cosmic_signature_exclusions(
  cancer_type = NULL,
  treatment_naive = NULL,
  quiet = FALSE
)

cancer_type: See here for supported cancer type labels.
treatment_naive: give TRUE if samples were taken pre-treatment; FALSE or leave NULL otherwise.
quiet: (default false) for non-interactive use, suppress explanations and advice.

a vector of signatures to feed to the trinuc_mutation_rates()

signature_exclusions argument.